1.
blindness, being blind
The state of being unable to see. In modern usage, 盲目 as a literal medical term is increasingly avoided in favor of more respectful expressions.
2.
blind (figurative), uncritical, unreasoning
Being unable or unwilling to see the truth; accepting something without critical thought. The figurative sense is the most common use today.
Usage
The literal sense (sense 1) is used in literary, historical, and some formal contexts, but in everyday Japanese it is increasingly considered insensitive. More respectful alternatives include 目が不自由な方 or 視覚障害者.
The figurative sense (sense 2) is more freely used and is the primary modern usage. 盲目的 (blindly, uncritically) is the most common form in this sense.