1.
burnout, being burned out
A state of physical and mental exhaustion caused by prolonged stress or overwork, leaving a person feeling drained and unable to function effectively.
Usage
燃え尽き is the noun form of the verb 燃え尽きる (to burn out completely). While the verb can describe literal burning, the noun 燃え尽き is almost always used in the psychological/medical sense of burnout.
Common collocations
Cultural note
真っ白に燃え尽きた (burned out to pure white ash) echoes the famous last scene of the boxing manga あしたのジョー, and is a stock phrase for having given everything.