1.
to become fed up with, to grow weary of, to become disgusted with
To reach a point where one can no longer tolerate something due to frustration, boredom, or repeated negative experiences.
Pattern: 〜に嫌気が差す
The thing one is fed up with is marked by に.
Forms
Usage: This expression conveys a sense of accumulated frustration or dissatisfaction. It often implies that the feeling built up over time rather than arising suddenly. Frequently used when explaining a motivation for change, such as quitting a job or leaving a place.