1.
so; therefore; and so
At the start of a sentence, なので links to the previous statement and introduces its result or conclusion, much like "so" or "that's why" in English.
2.
because (it) is; since (it) is
Following a noun or na-adjective, なので gives a reason (the copula な plus the particle ので). It states a cause more softly and politely than だから.
Sentence-initial なので (sense 1) is common in casual writing and speech, though some prescriptivists dislike starting a sentence with it; in formal writing そのため or したがって is preferred.
After a noun or na-adjective (sense 2), use な before ので: 学生なので, 元気なので. After plain-form verbs and i-adjectives, use ので alone: 行くので, 高いので.