1.
load; baggage; cargo
Goods or baggage being carried or transported. Often appears in compounds such as 荷物 (luggage) rather than as a standalone word in modern speech.
2.
burden; responsibility
Figuratively, a weight of responsibility or worry that one must bear. Used in set expressions about feeling burdened or relieved.
Standalone 荷 is somewhat literary; most everyday uses appear in compounds or set expressions. The figurative 'burden' sense is the more common standalone use today.