四 + 百. Both parts keep their normal shape.
Pronunciation
Only three of the hundreds change:
All the others, including 四百, are regular.
The older reading しひゃく survives only in a few set expressions such as 四百四病 (the ills that flesh is heir to). For counting, always say よんひゃく.
Common collocations
- 四百字詰め原稿用紙: the standard 400-character manuscript sheet
- 四百メートル走: the 400-meter dash