1.
at most, at best
Indicating the upper limit of what can be expected; no more than.
2.
as much as possible, to the best of one's ability
Doing something with maximum effort (often with slight resignation or irony).
精々 is an adverb with two main nuances: setting an upper limit ("at most") and doing one's best (sometimes with an ironic edge).
Meaning 1 - upper limit
Sets a ceiling, implying the actual amount is less than expected.
Meaning 2 - ENCOURAGEMENT/IRONY
When used to mean "do your best," it often carries a slightly dismissive or ironic tone, depending on context.
Writing
Usually written in hiragana (せいぜい). The kanji 精々 is uncommon.
Similar words
Related Words
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少なくとも (at least)
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せめて (at least)
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多くとも (at most)
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たかが (merely)